INBRIJA (levodopa inhalation powder), 42 mg capsules

Bob's Real INBRIJA® Story

(DESCRIPTION)

[Bob shows his hands, which are shaking]

(BOB)

My hands are not working properly.

(DESCRIPTION)

[Bob holds up both hands and squeezes them]

(BOB)

I can barely feel them.

(TITLE CARD)

While cameras were rolling, Bob delayed using his as-needed medication

(DESCRIPTION)

[Bob’s feet are shuffling across the floor]

(BOB)

My uh, feet are shuffling and it’s hard to take a normal step.

(TITLE CARD)

to give you a glimpse of what it’s like when his Parkinson’s symptoms return

(DESCRIPTION)

[Bob sits in a chair and talks to the camera]

(BOB)

My face feels very stiff. umm.

(DESCRIPTION)

[Bob looks at camera then closes eyes and takes a deep breath]

(BOB)

(breathing)

(TITLE CARD)

Bob found that the return of his Parkinson’s symptoms

(OFF periods) disrupted his day

(DESCRIPTION)

[Bob sits in a chair and talks to the camera motioning with his hands]

(BOB)

Generally speaking, when an OFF period starts to happen to me, I feel it in my hands. I lose dexterity in my hands.

(ON SCREEN TEXT)

Bob

Support group leader and Tai Chi instructor

(DESCRIPTION)

[Camera zooms in on Bob’s hands]

(BOB)

I can’t feel what I’m holding.

(DESCRIPTION)

[Bob sits in chair talking to camera holding up hands]

(BOB)

Also, my feet tend to shuffle.

(DESCRIPTION)

[Bob talks to the camera]

(BOB)

The thing that bothers me most about an OFF period...

(DESCRIPTION)

[Bob sits in a chair talking to the camera and motions with his hands]

(BOB)

is not necessarily a physical feeling in my body. It’s a feeling of...

(DESCRIPTION)

[Bob’s wife holds his hand and helps him walk to the table]

(BOB)

vulnerability. It’s a feeling of weakness. It’s a feeling of having a disease and that’s hard, because you get to do it every time you go OFF, which could be three, four times a day, and face that reality of what’s happening to your body.

(TITLE CARD)

Bob then discovered that he no longer needed to “power through” on his own

(DESCRIPTION)

[Bob sits in a chair talking to the camera]

(BOB)

I found out about INBRIJA from talking with my doctor...

(ON SCREEN TEXT)

INBRIJA® (levodopa inhalation powder, 42 mg capsules) is a prescription medicine used when needed for OFF episodes in adults with Parkinson’s treated with regular carbidopa/levodopa medicine.

(DESCRIPTION)

[Bob is in the passenger seat of the car his wife is driving]

(BOB)

at my annual visit. He...

(ON SCREEN TEXT)

INBRIJA® (levodopa inhalation powder, 42 mg capsules) is a prescription medicine used when needed for OFF episodes in adults with Parkinson’s treated with regular carbidopa/levodopa medicine.

(DESCRIPTION)

[Bob’s wife pulls their car into a parking spot]

(BOB)

...turned to me and said,

(ON SCREEN TEXT)

INBRIJA® (levodopa inhalation powder, 42 mg capsules) is a prescription medicine used when needed for OFF episodes in adults with Parkinson’s treated with regular carbidopa/levodopa medicine.

(DESCRIPTION)

[Bob’s wife pulls their car into a parking spot]

(BOB)

Bob, I’ve got a drug that...

(ON SCREEN TEXT)

INBRIJA does not replace regular carbidopa/levodopa medicine.

(DESCRIPTION)

[Bob opens the gate on a fence]

(BOB)

would help manage the OFF symptoms.

(ON SCREEN TEXT)

INBRIJA does not replace regular carbidopa/levodopa medicine.

(DESCRIPTION)

[Bob walks around an indoor pool]

(BOB)

Currently, I’m using INBRIJA three times a day, within my discretion. I take it depending on what my needs are.

(DESCRIPTION)

[Bob’s wife talks to the camera]

(CECILY)

I try to remind him to take his...

(ON SCREEN TEXT)

Cecily

Bob’s wife and care partner

Do not use INBRIJA if you take or have taken a nonselective monoamine oxidase inhibitor such as phenelzine or tranylcypromine within the last 2 weeks.

(DESCRIPTION)

[Bob’s wife talks to the camera]

(CECILY)

INBRIJA at the beginning of an OFF period so that his symptoms don’t get too bad.

(ON SCREEN TEXT)

Cecily

Bob’s wife and care partner

Do not use INBRIJA if you take or have taken a nonselective monoamine oxidase inhibitor such as phenelzine or tranylcypromine within the last 2 weeks.

(DESCRIPTION)

[Bob sits down in a chair in front of a group of people in a gymnasium]

(BOB)

If you have Parkinson’s and are already taking...

(ON SCREEN TEXT)

INBRIJA is for use as needed for the return of symptoms (OFF periods)

(DESCRIPTION)

[Bob lifts his leg up and stretches out his foot]

(BOB)

carbidopa levodopa,

(ON SCREEN TEXT)

INBRIJA is for use as needed for the return of symptoms (OFF periods)

(DESCRIPTION)

[Bob practices Tai Chi]

(BOB)

INBRIJA is an inhaled form of...

(ON SCREEN TEXT)

INBRIJA is for use as needed for the return of symptoms

(OFF periods)

(DESCRIPTION)

[Bob walks around a group of people practicing Tai Chi]

(BOB)

levodopa you can use when needed for OFF periods.

(DESCRIPTION)

[Bob practices Tai Chi with a group of people]

(BOB)

Just remember, INBRIJA doesn’t replace your regular carbidopa/levodopa medicine.

(DESCRIPTION)

[Close-up of Bob’s hands shaking]

(BOB)

I’m currently experiencing an OFF period.

(ON SCREEN TEXT)

Please see the accompanying Instructions For Use.

(DESCRIPTION)

[Close up of Bob’s right hand shaking]

(BOB)

I’m gonna go take my INBRIJA right now.

(ON SCREEN TEXT)

Please see the accompanying Instructions For Use.

(DESCRIPTION)

[Bob opens foil blister package of capsule]

(ON SCREEN TEXT)

Please see the accompanying Instructions For Use.

(DESCRIPTION)

[Bob loads capsule into the inhaler]

(BOB)

I take two capsules per OFF period when...

(ON SCREEN TEXT)

Do not orally inhale more than 1 dose (2 capsules) for any OFF period. Do not take more than 5 doses (10 capsules) in a day.

(DESCRIPTION)

[Bob puts inhaler mouthpiece into his mouth]

(BOB)

I feel my Parkinson’s symptoms...

(ON SCREEN TEXT)

Do not orally inhale more than 1 dose (2 capsules) for any OFF period. Do not take more than 5 doses (10 capsules) in a day.

(DESCRIPTION)

[Bob takes deep breath from inhaler and then breathes out]

(BOB)

start to return. If you are taking INBRIJA, the most common side effects that you may experience are cough, an infection of the nose,

(ON SCREEN TEXT)

Do not orally inhale more than 1 dose

(2 capsules) for any OFF period. Do not take more than 5 doses

(10 capsules) in a day.

(DESCRIPTION)

[Bob opens another capsule foil blister package]

(BOB)

throat, or sinuses,

(ON SCREEN TEXT)

The most common side effects of INBRIJA are cough, upper respiratory tract infection, nausea, and change in the color of saliva or spit.

(DESCRIPTION)

[Bob loads capsule into inhaler]

(BOB)

nausea and a change in the...

(ON SCREEN TEXT)

The most common side effects of INBRIJA are cough, upper respiratory tract infection, nausea, and change in the color of saliva or spit.

(DESCRIPTION)

[Bob takes a breath from the inhaler]

(BOB)

color of saliva or spit. My doctor checked...

(ON SCREEN TEXT)

The most common side effects of INBRIJA are cough, upper respiratory tract infection, nausea, and change in the color of saliva or spit.

(DESCRIPTION)

[Bob exhales]

(BOB)

with me that I didn’t have asthma, COPD, or any...

(ON SCREEN TEXT)

People with asthma, COPD, or other lung diseases may wheeze or have difficulty breathing after inhaling INBRIJA. If this occurs, stop taking INBRIJA and seek immediate medical attention.

(DESCRIPTION)

[Bob places cap on the inhaler]

(BOB)

other chronic lung disease.

(ON SCREEN TEXT)

People with asthma, COPD, or other lung diseases may wheeze or have difficulty breathing after inhaling INBRIJA. If this occurs, stop taking INBRIJA and seek immediate medical attention.

(TITLE CARD)

INBRIJA may start working in as soon as 10 minutes...

(DESCRIPTION)

[Bob talks to another man]

(BOB)

I’m feeling much better now that I’ve taken INBRIJA.

(DESCRIPTION)

[Car pulls into driveway]

(BOB)

The rigidity in...

(DESCRIPTION)

[Bob buttons his shirt]

(BOB)

my hands are starting to go away...

(DESCRIPTION)

[Bob goes to mailbox and opens it]

(BOB)

and now I have more feeling...

(DESCRIPTION)

[Bob takes mail out of mailbox and walks back towards his house]

(BOB)

and now I’m back on.

(DESCRIPTION)

[Bob takes out a coffee filter]

(BOB)

OFF periods can...

(DESCRIPTION)

[Bob scoops coffee grounds out of a container]

(BOB)

disrupt my life. I’ve...

(DESCRIPTION)

[Bob pours water into coffee-maker]

(BOB)

chosen not to sit around and wait.

(DESCRIPTION)

[Bob and his wife clink their coffee cups together]

(BOB)

So I just go and do the best I can with what I’ve got...

(DESCRIPTION)

[Car drives through a development]

(BOB)

and push along as hard and as fast as I can.

(TITLE CARD)

If you have Parkinson’s, are taking carbidopa/levodopa, and

are experiencing a return of symptoms,

(TITLE CARD)

Ask your doctor if INBRIJA may be right for you...

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(VOICE OVER)

Additional Important Safety Information

Before using INBRIJA, tell your healthcare provider about your medical conditions, including:

Tell your healthcare provider if you take:

Do not drive, operate machinery, or do other activities until you know how INBRIJA affects you. Sleepiness and falling asleep suddenly can happen as late as a year after treatment is started.

Tell your healthcare provider if you experience the following side effects:

Please see accompanying Patient Information Leaflet.

(SUPER)

Visit INBRIJA.com to learn more.

(SUPER)

INBRIJA, and the INBRIJA logos are all trademarks of Acorda Therapeutics, Inc.

©2020 Acorda Therapeutics, Inc. All rights reserved. 2/20 INB8692

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View the referenced video

02/21 INB9148